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Dengue And Other Hemorrhagic Fevers: Towards A First Potential Treatme IRD immuno-virologists and their research partners have determined the mechanisms involved in the occurrence of the vascular leakage triggered by the Dengue virus. Metalloproteinases are responsible for the passage of plasma across the blood-vessel walls. These original results, validated first by in vitro tests then in vivo on a mouse model, open up the first line of attack for treatment against hemorrhagic Dengue and new perspectives for others hemorrhagic fevers, such as Ebola. Unusual Material That Contracts When Heated Is Giving Up Its Secrets T Most solids expand when heated, a familiar phenomenon with many practical implications. Among the rare exceptions to this rule, the compound zirconium tungstate stands out by virtue of the enormous temperature range over which it exhibits so-called "negative thermal expansion,"contracting as it heats up and expanding as it cools, and because it does so uniformly in all directions. New Insight Into The Link Between Genetics And Obesity Scientists have acquired new insight into how the 'obesity gene'triggers weight gain in some individuals. Their findings could have implications for the future treatment of obesity as well as adult-onset diabetes. CK2 Protein Sustains Colon Cancer Cells By Sabotaging Ability To Commi A protein called CK2 plays a deadly role in colorectal carcinoma by blocking the ability of these tumors to activate a natural self-destruct mechanism that would clear this cancer from the body. Today's Babies Are Fatter Babies By examining more than 120,000 children under age six in Massachusetts over 22 years, a newly published study shows that young children -- especially infants -- are now more likely to be overweight. This study was based at the Department of Ambulatory Care and Prevention of Harvard Medical School and Harvard Pilgrim Health Care and appears in the July issue of Obesity. Brain Abnormalities Underlying Key Element Of Borderline Personality D Using new approaches scientists have gained a view of activity in key brain areas associated with a core difficulty in patients with borderline personality disorder -- shedding new light on this serious psychiatric condition. Holiday Reading for Scientists I’ve allowed a stack of books to accumulate on my desk over the last few weeks, some of them I’ve glanced through, others I’ve devoured over the course of a few days in snatched moments between writing, researching, blogging, and fixing web site servers. Some of them are inflammatory others are a bit of a [...] Arthritis: What Wnt Wrong? The cellular signaling protein Wnt, which is involved in embryonic development and cancer, contributes to disease progression of both rheumatoid arthritis and osteoarthritis. The article by Nakamura et al., "Expression profiles and functional analyses of Wnt-related genes in human joint disorders,"appears in the July issue of The American Journal of Pathology and is accompanied by a commentary. Mayo Clinic Article Offers Data About Shingles Virus When a vaccine to prevent shingles was approved for use in 2006, the Food and Drug Administration recommended the vaccine for people age 60 and older who previously had chickenpox. But two issues -- the vaccine's cost and the perception that shingles primarily affects adults with weakened immune systems -- have left some physicians undecided about whether healthy adults need the vaccine. [Scary] Cruise Passengers with Broken Bones Come Ashore Nearly 500 passengers including eight with broken bones disembarked from the "Grand Voyager"cruise ship in Sardinia Tuesday a day after it was battered by a storm in the Mediterranean Sea.
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