In the News
Treating Individuals: How Generalizable Are Trial Data?
The Lancet is running a five-part series about clinical trial data and its applicability to individual patients. Lost In The Middle: Author Order Matters, New Paper Says
With research typically being conducted by large teams of scientists, it is now commonplace for a paper to boast as many authors as a basketball team's starting lineup. According to a new study, credit for those papers is far from evenly distributed, and the order in which the authors'names appear can make the difference between who receives tenure and who does not. Burning Fat And Carbohydrate During Exercise
Fat oxidation during exercise reflects a fine interplay between the cardiovascular, neurological, endocrine and muscle metabolic systems. During exercise and physical activity, the primary fuels used by muscles are carbohydrate and fat. When mild exercise is performed there is a tendency to burn relatively more fat and less glucose, but as exercise becomes more intense, a higher fraction of the energy demands of the muscle are supplied by glucose, until at the highest intensities almost only carbohydrates are used. Mayo Clinic Researchers Use Ultrasound To Describe Subtle Heart Muscle
By using sound waves Mayo Clinic researchers have described subtle changes in the motion of the heart that are measurable by ultrasound and may improve understanding of heart function, and possibly be a noninvasive aid in predicting impending heart damage including heart attacks. The study could also contribute to optimal adjustment of cardiac pacemakers or perhaps better design of artificial hearts. Scientists Focus On 'Dwarf Eye' -- Genetic Finding May Have Implicatio
Working with an Amish-Mennonite family tree, Johns Hopkins Wilmer Eye Institute researchers have discovered what appears to be the first human gene mutation that causes extreme farsightedness. In the July 5 issue of the Proceedings of the National Academy of Sciences, the researchers report that nanophthalmos, or "dwarf eye,"a rare, potentially blinding disorder, is caused by an alteration in a gene called MFRP that helps control the eye's growth, shape and focus. Side Effects Of Cholesterol-lowering Drugs
In a report published in the online issue of Circulation: Journal of the American Heart Association, (May 24, 2005), researchers said the cholesterol-lowering drug rosuvastatin (Crestor) was more likely to be associated with muscle damage (myopathy) compared to atorvastatin (Lipitor), simvastatin (Zorcor) and pravastatin (Pravachol). North Atlantic Warming Tied To Natural Variability
A new analysis of available records shows that while the North Atlantic Ocean's surface waters warmed in the 50 years between 1950 and 2000, the change was not uniform. In fact, the subpolar regions cooled at the same time that subtropical and tropical waters warmed. This striking pattern can be explained largely by the influence of a natural and cyclical wind circulation pattern called the North Atlantic Oscillation. NIST Issues Call For A New 'Hash'Algorithm
NIST has opened a competition to develop a new cryptographic hash algorithm, a tool that converts a file, message or block of data to a short "fingerprint"for use in digital signatures, message authentication and other computer security applications. Cancer Gene Drives Pivotal Decision In Early Brain Development
A gene linked to pediatric brain tumors is an essential driver of early brain development, researchers have found. The study reveals that the neurofibromatosis 1 (NF1) gene helps push stem cells down separate paths that lead them to become two major types of brain cells: support cells known as astrocytes and brain neurons. AMPA Receptors On Cell Membrane Make Us Smarter
AMPA receptors are an important regulating factor in the connection between our nerve cells. However, researchers have demonstrated that it is not the amount of AMPA receptors inside the cell that are vitally important but the receptors located on the cell membrane. Changes in the strength of the connections between two nerve cells form the basis of our ability to learn.
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