In the News
'Epigenetics' Means What We Eat, How We Live And Love, Alters How Our
A mother rat withholds nurturing licks from its pup and elicits a brain change that impairs the pup's response to stress as an adult, researchers in Canada found. A pregnant woman's dietary deficits increase her offspring's risk of diabetes, stroke and heart disease later in life, researchers in England have shown. Mechanism Proposed For Link Between RU-486 And Fatal Infections
The abortion drug mifepristone (Mifeprex,TMRU-486) has been linked to rare cases of fatal bacterial infections, but until now the connection has not been clearly understood. In "Pathophysiology of mifepristone-induced septic shock due to Clostridium sordellii,"author and Brown University professor Ralph P. Miech, MD, PhD, proposes two models of how this devastating reaction may occur. The article appears in The Annals of Pharmacotherapy Online and in the journal's upcoming September print issue. Get Ready for the New ISBN!
"The new 13-digit ISBN [International Standard Book Number] has been approved and plans are underway to transition to the new number industry-wide, world-wide by January 1, 2007. Find out how the expansion of the ISBN from 10-digits to 13-digits will impact your business and operations."Includes information for publishers and librarians and links to related sites. From the National Information Standards Organization (NISO). Prostate Leading Newly Diagnosed Cancer Among Men; Breast Cancer Leads
The most comprehensive federal report available on state-specific cancer rates shows prostate cancer is the leading cancer diagnosed overall in men in the United States and breast cancer is the most common form of cancer diagnosed in U.S. women. The leading cause of cancer death for both men and women is lung cancer. Tissue Stiffness Drives Tumor Formation
Researchers at the University of Pennsylvania School of Medicine have shown that tumor formation is generated by a complex interaction of both mechanical as well as chemical signals, and the resulting tissue stiffening induces molecular signals that promote the cancerous behavior of cells. Force, growth, and tumor behavior are inextricably linked and this enhanced understanding of the necessary fusion of these factors may lead to the development of new tumor therapies or targets. Over 700,000 Children Die Needlessly Every Year In The Eastern Mediter
Over 700,000 babies and children could be saved every year in the Eastern Mediterranean region if countries adopted some simple low cost health measures, say researchers in this week's British Medical Journal. Rapid Restoration Of Immunity In Immune-suppressed Cancer Patients Usi
Researchers at the University of Pennsylvania School of Medicine found that protective levels of immunity against pneumococcus could be obtained in immune-suppressed myeloma patients who were given a prophylactic bacterial vaccine in addition to a new autologous T-cell-based vaccine only two weeks after their stem-cell transplantation. They will apply the principles learned from this study to hone the development of a cancer vaccine aimed directly at tumors and other cancers. Anthropologists Find 4.5 Million-year-old Hominid Fossils In Ethiopia
Scientists from Indiana University Bloomington and seven other institutions have unearthed skeletal fossils of a human ancestor believed to have lived about 4.5 million years ago. The fossils, described in this week's Nature (Jan. 20), will help scientists piece together the mysterious transformation of primitive chimp-like hominids into more human forms. Diabetes Drugs Increase Risk Of Heart Failure, Research Shows
A class of drugs commonly used to treat type 2 diabetes may double the risk of heart failure, according to a new analysis. Based on a review of research studies and case reports involving more than 78,000 patients, the authors concluded that the risk of heart failure may be up to 100 percent higher (depending on the type of study) in patients taking thiazolinediones (which includes Avandia®and Actos®). Financial Incentives May Hold Key To Cutting Child Malaria Deaths
Giving small financial incentives to health workers in low-income countries may hold the key to reducing the huge death toll from malaria in young children, according to a new article. Staff training alone is not a solution, so researchers evaluated whether training, together with availability of drugs and small financial incentives, could save lives.
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