Midland Main Line

The Midland Main Line is a main railway line in the United Kingdom and is part of the British railway system.

The line links London (St Pancras) to Sheffield (Midland Station) in northern England, but also links other important population centres including Luton, Bedford, Wellingborough, Kettering, Market Harborough, Leicester (London Road), Loughborough, Long Eaton, Derby, Beeston, Nottingham and Chesterfield. The line is electrified between London and Bedford. And there are plans to build a station on the line to service East Midlands Airport.

Towards the London end the lines are also used for Thameslink services.

The Midland Main line was built between the 1830s and the 1860s largely by the Midland Railway company, the Leicester to London stretch of the line was built in the 1860s to relieve an earlier route to London via Rugby which had been built by the Midland Railway's predecessor the Midland Counties Railway and had become very congested.

The express services on the line are operated by a company called Midland Mainline.



In the News

Genetic Defects Give The Immune System The Green Light To Attack The P
Scientists at Joslin Diabetes Center have found genetic regions that, when defective, allow the immune system to attack the pancreas -- the first in a series of mis-steps that lead to type 1 diabetes. Armed with these findings, published today, March 22, in the journal Immunity, the researchers are now trying to hone in on the exact genes involved, in mice and in human patients.

In The Mating Game, Male Wild Turkeys Benefit Even When They Don't Get
For wild turkeys, at least, helping your brother find a willing and eager mate is a better way to pass on your genes than chancing the mating game alone, according to a new study by a University of California, Berkeley, graduate student.

Education Linked To Risk Of Cancer Death
A new American Cancer Society study finds having at least some education beyond high school is strongly associated with a decreased risk of cancer death. For all cancer sites combined, death rates among white and black men with the lowest (0-8 years) level of education were about three times higher than those with the highest (17+ years) level of education.

Suppressing Growth Hormone In Early Adulthood May Prevent Cancer
A modest suppression of growth hormone and related compounds beginning in early adulthood may delay the onset or progression of several types of cancer, researchers from Wake Forest University School of Medicine and other centers reported today at ENDO 2005, the annual meeting of the Endocrine Society, in San Diego.

Screening MRI Allows Detection Of More Breast Cancers In High-risk Wom
Magnetic resonance imaging enables radiologists to accurately identify tumors missed by mammography and ultrasound, according to a multicenter study comparing the three screening methods in women at high-risk for breast cancer.

Breast Cancer Linked To Pesticide DDT, Study Suggests
High levels of the primary component of DDT, in women exposed before mid-adolescence, were found to be predict a five-fold increase in breast cancer risk. Many American women heavily exposed to DDT in childhood have not yet reached 50 years of age, therefore the public health significance of DDT exposure in early life may be large.

[Scary] Pregnant woman says 'maternal instinct' helped her kill attack
FORT MITCHELL, Ky. - A pregnant woman who killed her attacker said a maternal instinct helped her fight off the woman who investigators believe was after her unborn child."I do believe that I fought harder because it was for my child,"Sarah Brady told ABC's "Good Morning America"in interviews aired Sunday and Monday. "It is a maternal instinct to protect your child to the very end."Katherine Smith, 22, died Thursday after luring Brady to her apartment to pick up a package supposedly delivered to the wrong address. When Smith pulled out a knife and attacked the pregnant woman, Brady fought back, striking Smith on the head with an ash tray and stabbing her three times with her own knife, police said. Brady, 26, said she didn't know Smith before the two met at Smith's apartment and can't be certain why Smith wanted to kill her."I really am not sure what was going through her mind,"Brady told ABC. "The only thing I thought was that she was going to kill me and my child and that is the only thing that ran through my mind."

Major Visual Disorders In People Over 40 May Be Costing U.S. Economy B
Major visual disorders in Americans older than 40 years may cost the U.S. economy an estimated $35.4 billion a year, according to a report in the December issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

Researchers Work To Track North American Climate Change
Scientists will run computerized climate models to see how climate change may affect North America or even individual states. Gene Takle, one of the researchers, begins talks about climate change with some strong statements. "There is no question now that the climate is changing on a global scale,"says Takle, a professor of geological and atmospheric sciences and agronomy. "The evidence is so overwhelming."

Damaging Inflammatory Response Could Hinder Spinal Cord Repair
The inflammatory response following a spinal cord injury appears to be set up to cause extra tissue damage instead of promoting healing, new research suggests. Scientists analyzing this inflammatory response in mice discovered that the types of cells recruited to the site of the injury are dominated within a week by those that promote inflammation. When chronic, inflammation can prevent healing, and these inflammatory cells are believed to remain at the injury site indefinitely.




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