In the News
Pro-inflammatory Enzyme Linked To Diabetes; Immune System's Macrophage An enzyme that initiates inflammation has been directly linked to insulin resistance and resulting type II diabetes by researchers at the UCSD School of Medicine. In addition, the team suggests that inhibition of the enzyme in the immune system's macrophages may be a new diabetes therapy. Holographic Movies Show Promise For Medical, Military Applications In a small research laboratory at UT Southwestern Medical Center, a grainy, red movie of circling fighter jets emerges from a table-top black box, while nearby, a video of a rotating human heart hangs suspended in a tank of gooey gel.These images -- the first true, three-dimensional, holographic movies -- are the brainchild of Dr. Harold "Skip"Garner, professor of biochemistry and internal medicine at UT Southwestern. Research Could Lead To New Drugs For HIV The increased frequency of drug resistance in isolates of the AIDS virus, HIV, makes identification of new antiviral targets an urgent necessity. Host genes required to support the replication of HIV are a potential source of such novel targets. A new study, conducted by Dr. Suzanne Sandmeyer and colleagues at the University of California, reports the discovery of over 100 host genes that affect the replication of a model retrovirus. One Giant Leap For Space Fashion: MIT Designs Sleek, Skintight Spacesu In the 40 years that humans have been traveling into space, the suits they wear have changed very little. The bulky, gas-pressurized outfits give astronauts a bubble of protection, but their significant mass and the pressure itself severely limit mobility. MIT Professor Dava Newman wants to change that. Newman is working on a sleek, advanced suit designed to allow superior mobility when humans eventually reach Mars or return to the moon. Micro RNAs And Musculature In an effort to understand the biological function of the microRNA mir1, Drs. Nicholas Sokol and Victor Ambros (Darmouth Medical School) have studied the expression profile, transcriptional regulation and loss-of-function phenotype of Drosophila mir-1 (Dmir-1). Strikingly, their study shows that, in Drosophila embryos, mir-1 expression is not required for mesodermal cell fate decisions or cell proliferation during embryogenesis, but rather, that it appears to act to reinforce and maintain cell identity during times of rapid growth. New Frontier Opens In The Search For Life On Other Planets Scientists recently discovered a new frontier in the race to find life outside our solar system. Dying red giant stars may bring icy planets back from the dead. Once-frozen planets and moons may provide a new breeding ground for life as their stars enter the last, and brightest, phase of their lives. Previous ideas about the search for extra-solar life had excluded these regions. Researchers Discover Possible Cause Of Thrombosis A team of researchers from the CIMA of the University of Navarra has discovered a possible cause of thrombosis, and has developed a new diagnostic test for this disease. Tumor Individuality Useful For Guiding Rational Chemotherapeutic Decis A new study describes in detail exactly how the chemotherapeutic drug paclitaxel induces cell death in tumor cells and how common mutations in human tumors confer drug resistance, and demonstrates that combination treatment can restore therapeutic effectiveness of the drug. The Numbers Behind The Kidney: Mathematicians Find A Useful Niche In B Mathematics professor Harold Layton was an unusual graduate student back in the 1980s. While the other Duke students stuck to theorems and proofs, Layton turned his attention to something more ordinary: urine. For his dissertation he created a mathematical model of how the kidney combines water and waste to produce the familiar yellow stream. Childhood Kidney Disorder Has Lasting Effects A kidney condition that can arise in children and was until recently believed to disappear after puberty may persist into adulthood and cause significant long-term complications, according to a new study. The findings indicate that better treatment options are needed for children with the disorder, called minimal change nephrotic syndrome.
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