Practical limits for obtaining knowledge
What we hold to be knowledge is often derived by a combination of reason from either traditional, authoritative, or scientific sources. Many times such knowledge is not verifiable; sometimes the process of testing is prohibitively dangerous or expensive. For instance, some physics theories about the nature of the universe, such as string-theory, requite the construction of testing equipment currently beyond our technology. Since such theories are in principle subject to verification or refutation, they are scientific; since they are not proven experimentally, they are not considered certain knowledge. Rather, in such cases we have certain knowledge only of the theory, but not of what the theory describes.
"Of the three ways in which men think that they acquire knowledge of things - authority, reasoning, and experience - only the last is effective and able to bring peace to the intellect." (Roger Bacon, English alchemist and philosopher)
See also: Epistemology -- Truth -- Wisdom -- Understanding
Semi-related topics: Data -- Information -- Knowledge creation -- Knowledge Management -- Knowledge transfer -- Instructional capital -- Tacit knowledge