In the News
Scientists Develop A New Way To Target Alzheimer's Disease
A group of scientists at NYU School of Medicine have devised a way to reduce amyloid beta deposition by interfering with the deadly embrace of these proteins. Resistance is not futile
As antibiotics fall to bacterial resistance one by one, it is essential that medicinal chemists keep ahead of the game by finding compounds with new modes of attack. Recently a new antibiotic, platensimycin has been found to act potently through a novel mechanism. Now, US chemists have devised a total synthesis for this unique compound [...] New Force-fluorescence Device Measures Nanometer-scale Motion
A hybrid device combining force and fluorescence has made possible the accurate detection of nanometer-scale motion of biomolecules caused by pico-newton forces. [Ironic] An Italian pensioner committed suicide after his wife fell in
Recalling the end of Romeo and Juliet, the 70-year-old man, Ettore, who had sat by his wife's bedside for four months after she slipped into a coma following a heart attack, finally gave up hope and gassed himself in the garage of his family home.Less than a day later, his wife, Rossana, woke up in her hospital bed in Padua and immediately asked for him. Jefferson Researcher's Results Show Promise For Metastatic Eye Melanom
When melanoma of the eye spreads to the liver, patients have few good options. Surgery is frequently impossible, and chemotherapy hasn't proven effective. But now, by simultaneously revving up the immune system and choking off the tumor's oxygen supply, oncologists at Jefferson Medical College have shown promising results from an early, phase 1-2 clinical trial of a novel treatment for uveal melanoma that has spread to the liver. Measles Deaths Worldwide Drop By Nearly 40% Over Five Years
The World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) today announced that countries are on target to halve deaths from measles, a leading vaccine-preventable killer, by the end of this year. Global measles deaths have plummeted by 39%, from 873,000 in 1999 to an estimated 530,000 in 2003. Breath Test Offers Hope For Early Detection Of Lung-bacteria Growth In
Breath-analysis testing may prove to be an effective, non-invasive method for detecting the damaging lung-bacteria growth seen in cystic fibrosis, which would allow for early stage treatments that can extend the health of people with this disease, UC Irvine researchers have found. Researchers Channel Microcapsules Into Tumour Cells And Release Their
Medicines are most helpful when they directly affect the diseased organs or cells -- for example, tumour cells. Max Planck scientists have come one step closer to that goal: they have intentionally released a substance in a tumour cell. The scientists placed the substance in a tiny capsule which gets channelled into cancer cells, and is then "unpacked"with a laser impulse. Sleep, And How Cocaine Changes The Brain To Make Treatment So Difficul
New research clarifies the role of drugs of abuse on sleep, why cocaine is so powerful, and the brain changes that occur due to abuse that make addiction so difficult to treat. Studies have found that addictive drugs such as cocaine affect many circadian, or biological clock, genes including two which have been shown to regulate dopamine, a brain chemical that underlies the rewarding effects of cocaine. Scientists Investigate Initial Molecular Mechanism That Triggers Neuro
Chemists have solved a decade-long molecular mystery that could eventually help scientists develop drug therapies to treat a variety of disorders, including epilepsy and Alzheimer's disease. Using intensive theoretical and computational calculations, researchers have modeled the initial molecular changes that occur when the neurotransmitter glutamate docks with a receptor on a neuron, which sets in motion a chain of events that culminates in the neuron firing an electrical impulse.
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