Tootsie

Tootsie is a 1982 comedy film which tells the story of an actor who can't get roles, until he dresses like a woman and becomes the star of a soap opera. It stars Dustin Hoffman, Jessica Lange, Teri Garr, Dabney Coleman, Charles Durning, Bill Murray, Sydney Pollack, George Gaynes and Geena Davis.

The movie was adapted by Larry Gelbart, Barry Levinson (uncredited), Elaine May (uncredited) and Murray Schisgal from the story by Gelbart and Don McGuire. It was directed by Pollack.

It won an Academy Award for Best Actress in a Supporting Role (Jessica Lange) and was nominated for Best Actor in a Leading Role (Dustin Hoffman), Best Actress in a Supporting Role (Teri Garr), Best Cinematography, Best Director, Best Film Editing, Best Music, Song (for Dave Grusin, Alan Bergman and Marilyn Bergman for It Might Be You), Best Picture, Best Sound and Best Writing, Screenplay Written Directly for the Screen. The movie was #62 on American Film Institute's 100 Years, 100 Movies and #2 on its 100 Years, 100 Laughs, and has been deemed "culturally significant" by the United States Library of Congress and selected for preservation in the National Film Registry.



In the News

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The U.S. Food and Drug Administration (FDA) has approved maraviroc, an antiretroviral drug for use in adult HIV patients. Maraviroc, sold under the trade name Selzentry, is the first in a new class of drugs designed to slow the advancement of HIV and received priority review by the FDA.

Steroid Discoveries Could Add Bulk To Crop Harvests
Taking steroids is a definite no-no for human athletes, but treating plants with steroids could offer performance enhancement of a more desirable nature by boosting the biomass and seed yields of crops. Unfortunately, plant steroids are complex, expensive chemicals, and the biological mechanisms by which they alter plant growth and development have remained largely a mystery.

New Brain Tumor Model Developed
A collaboration of researchers, led by Dr. Martine Roussel (St. Jude Children's Research Hospital), has developed a novel mouse model of medulloblastoma -- the most prevalent malignant pediatric brain tumor -- that the researchers hope will more accurately represent the genetic changes involved in human brain tumor development.

Electric Toothbrushes May Be Better At Fighting Plaque, Gum Disease
Powered toothbrushes with circular bristle heads that rotate in alternating directions are better at removing plaque and reducing the risk of gum disease than ordinary manual toothbrushes, a review of recent studies concludes.

Gone Fishing
In June, Wired magazine lost an extraordinary editor and human being, William Goggins. This month we remember his impact and legacy.

A Public Trust at Risk: The Heritage Health Index Report on the State
The report from a survey in December 2005 that concluded "immediate action is needed to prevent the loss of millions of irreplaceable artifacts"in libraries and museums. Areas of concern included permanent damage to items, lack of emergency planning, and conservation staffing. Also includes links to related information. From the Heritage Preservation and the Institute of Museum and Library Services.

MIT Researcher Presents New View Of How The Cortex Forms
How does the cortex, the brain's executive in charge of high-level thinking and planning, go from a uniform blob of brain matter to well-defined areas with specific sensing, cognition and movement tasks?

Firefox 2 Beta Arrives
The latest beta release of the next Mozilla Firefox browser is unleashed. Read our review. Plus: Having trouble finding a Firefox 2 download? We've got links. In Monkey Bites.

The Worldwide Guide to Movie Locations
"Have you ever wondered 'Where did they film that?' ... The Worldwide Guide to Movie Locations is the essential travel guide to filming locations of Hollywood blockbusters, indie cult films and arthouse cinema throughout the world."Browse by movie name, actor or director, or location. Also includes an interactive map for movies filmed in North London. From an author who has published books on the subject.

Penn Researchers Provide Recommendations For Artificial Nutrition And
For two decades, doctors have followed an ethically-established agreement about the appropriate use of artificial nutrition and hydration (ANH) for patients who are seriously ill or in a persistent vegetative state. The Terri Schiavo case -- which included very open, dramatic disagreements among family members over such considerations -- publicly challenged long-held agreements about ANH and caused many to question its proper use. In response to such challenges, researchers from the University of Pennsylvania's Institute on Aging and Center for Bioethics, and the Philadelphia VA's Center for Health Equity Research and Promotion review and clarify ethical principles regarding the use of ANH.


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