In the News
Tumor Individuality Useful For Guiding Rational Chemotherapeutic Decis
A new study describes in detail exactly how the chemotherapeutic drug paclitaxel induces cell death in tumor cells and how common mutations in human tumors confer drug resistance, and demonstrates that combination treatment can restore therapeutic effectiveness of the drug. A Vaccine Approach To Treating Parkinson's Disease
Researchers at the UCSD School of Medicine working with scientists at Elan Pharmaceuticals, have reported promising results in mice of a vaccine approach to treating Parkinson's and similar diseases. These results appear in the June edition of the journal Neuron. Vaginal Cancer Detected More Often With PET Than CT Scans
In patients with vaginal cancer, PET scans detected twice as many primary tumors and cancerous lymph nodes as did CT (computed tomography) scans, according to researchers at Washington University School of Medicine in St. Louis. At this time, however, Medicaid, Medicare and many private insurers specify CT for diagnosing and monitoring this cancer. The researchers hoping to encourage a change in that standard report their comparison of the two methods in the July 1 issue of the International Journal of Radiation Oncology. Pro-inflammatory Enzyme Linked To Diabetes; Immune System's Macrophage
An enzyme that initiates inflammation has been directly linked to insulin resistance and resulting type II diabetes by researchers at the UCSD School of Medicine. In addition, the team suggests that inhibition of the enzyme in the immune system's macrophages may be a new diabetes therapy. First Birth Using Pre-implantation Genetic Diagnosis To Save Baby From
Australian researchers announced that they have used pre-implantation genetic diagnosis (PGD) to avoid a couple having a baby suffering from rhesus factor disease -- the potentially fatal condition caused by incompatibility between a baby's blood and that of its mother. California Coastal Cleanup Day
This annual event held in mid-September "is the premier volunteer event focused on the marine environment in the country. On this day, 50,000 volunteers turn out to over 700 cleanup sites statewide to conduct what has been hailed by the Guinness Book of World Records as 'the largest garbage collection' (1993)."The site features a list of events around the state and material about the "Adopt-A-Beach"program. From the California Coastal Commission. Gene-transcription Machinery Seen Poised For Action, Held In Check Unt
For some time, scientists have been tracking down the sequence of biochemical steps required to attract and assemble at the head end of a gene the molecular machinery needed to transcribe that gene to put to work the information it encodes. New findings suggest that the gene-transcription machinery, once in place, can remain poised for action but held in check until a triggering signal sends it on its way down the linear DNA molecule. Deep Throat Revealed
A compilation of articles from the Washington Post about the May 2005 disclosure that "Deep Throat, the secret source whose insider guidance was vital to The Washington Post's groundbreaking coverage of the Watergate scandal, was a pillar of the FBI named W. Mark Felt."Includes information about reporters Bob Woodward and Carl Bernstein's interactions with Felt, editorials, photos, and related material. Requires free registration to view articles. Nietzsche: A Selected Annotated Bibliography
Research guide for the philosopher Friedrich Nietzsche, who "has been read in vastly different and contradictory ways. He has been appropriated by both the right and the left; read as a fascist and a socialist, a conservative and a revolutionary, a religious thinker and an atheist."The annotated bibliography covers letters, bibliographies, concordance, biographies, specific theories and works, and much more. From the New York Public Library. Skin Rash Actually Signifies Better Outcomes For Pancreatic And Lung C
The appearance of a rash in cancer patients treated with erlotinib (Tarceva) is strongly associated with longer survival, according to researchers from the drug's developer, OSI Pharmaceuticals, Inc. This is not the first time that rash has been associated with a survival advantage with EGFR inhibitors -- a class of drugs which includes erlotinib, cetuximab, panitumumab and others designed to block overproduction of the epidermal growth factor receptor -- but it is the most detailed analysis to date.
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